msdjoys
1 post
Jan 19, 2010
7:44 PM
|
I welcome advice. I was recently diagnosed with PD. I have been on Lexapro and Ativan for sleep on and off for years (am currently on it since last Sept). A couple of weeks ago I was put on Zocor (for a slightly elevated chol) and on Azilect 1mg and CoEnzyme Q10 1200mg for neuroprotection.
And yes, I now know I should not have added this many meds at once but... After several days of taking the new meds I started feeling tired and achy until about 3pm each day. I stopped the new meds (Azilect, CoEnzyme and Zocor) 3 days ago) hoping the symptoms would go away but the symptoms continue (tired - even though I think I'm sleeping well, harder to concentrate - till around 3pm, etc.). Any thoughts?
|
ThePharmacist
496 posts
Jan 23, 2010
2:43 PM
|
it is hard to say exactly, but here is my best guess. The zocor binds up liver enzymes in order to metabolize it. If you were taking the zocor in the evening, which most dr and pharmacists recommend, then taking the lexapro and/or ativan before bed, more than likely the blood levels of the lexapro and/or Ativan were greatly elevated. The zocor binds the enzymes so that any other meds taken a short time after will be metabolized into their active form and not be allowed to be broken down any more until some time later. The result is not that the lexapro and/or Ativan will be more effective, it will only result in the side effects of these medication to be more pronounced and more severe. Almost like a 1+1=3 effect. Even after you stop the zocor, the effect can be with you for days after. I would recommend takingbthe zocor in the afternoon, this should eliminate the problem.
First, I would start by adding the azilect in the morning, wait a week. If all is good, then add the Co-q, wait a week. If all is good, then add the zocor in the afternoon. Make sure to seperate the Co-Q for your other meds by at least a couple of hours. The true interactions of over the counter medications is not fully known.Best of health, Mark
|
Caroline42
122 posts
Jan 23, 2010
3:10 PM
|
Hi mark, ive heard neuros or perscriben that co enzyem Q10 for ET,wat doz it do? Thanks
|
ThePharmacist
504 posts
Jan 29, 2010
9:17 PM
|
co-q10 plays an important role in producing Adenosine Tri Phosphate(ATP). ATP is the major energy source in the cell that is responsible for muscle contraction. The addition of Co q 10 will help regulate the muscle contractions thus stabilizing the musscle tremor. Best of health, Mark
|
Caroline42
137 posts
Jan 30, 2010
2:40 PM
|
Ok mark sounds promisein :) thanks 4 info
|
ThePharmacist
509 posts
Jan 30, 2010
10:13 PM
|
you are welcome Best of health, Mark
|
maryfrances
2 posts
Feb 06, 2010
6:15 AM
|
What do you know about Azilect causing heart problems?
|
ThePharmacist
521 posts
Feb 18, 2010
1:31 PM
|
I have heard that issue. Exactly how real the link between azilect and heart issues, I don't know. I have not seen the data. I will also tell people that good news rarely makes news. It is usually the proposed bad news that does. Best of health, Mark
|
