rena moss
1 post
Oct 12, 2009
8:18 PM
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could you tell me the maximum daily dose of mirapex, as recommended to the neurologist by the drug mfg.
i have pd for about 5 years.
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MUSTANG
6 posts
Oct 13, 2009
5:43 AM
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Hi Rena, I have had PD for 6 years and have been on Mirapex. My neurologist said I am at the max with Mirapex which is 4.5mg per day. I would also like to hear from Mark to see what he says.
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ThePharmacist
386 posts
Oct 16, 2009
8:16 PM
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the max dose recommended by the drug company is 1.5 mg 3 times daily (4.5mg per day). The side effecys are ysyally dise related so at higher dises there may be mire side effects with not much more symptom relief. I have seen physicians use much more than this. The most I have seen is 21 mg per day in a very severe case. Best of health, Mark
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brooksie
206 posts
Oct 17, 2009
4:14 PM
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Just out of curiosity, may I ask why a doctor would prescribe 20 mg a day? Would this be done if Sinemet were not an option for a patient? Laura
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Dolores64
1 post
Oct 18, 2009
4:39 PM
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Just getting off Mirapex and having withdrawls...after much research found that RLS may be caused by salt yes
I mean table salt especially peanut butter...I had toast and peanaut butter before bed and thought I would go out of my mind. If sugar bothers Diabetis why cannot salt bother RLS. Good luck as everything has salt and drink all the water you can to flush your system out.
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ThePharmacist
391 posts
Oct 20, 2009
5:34 PM
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the high dose of mirapex was because (as I was told) that the patient had reactions to other medications and had a severe progression in a short period of time. Best of health, Mark
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rena moss
3 posts
Oct 30, 2009
5:00 PM
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thank you for your response.
the neuro prescibed 2mg 3 times a day for years.
i began to gamble. Loosing thousands. two visits to the neuro to discuss the gambling he basically told me to seek mental health professioinals, instead of lowering the mirapex to the maximum, which as you know is 4.5 daily. On my final visit to this doctor,he wrote a letter to a lawyer, (without my consent)telling him about the gambling and stating i needed a guardian. this doctor testified in probate court that
my decision making ability was impaired and in his
"expert opinion" i need a guardian. He cost me 50K in legal fees to get restored after living a nightmare for 2 years. He never lowered the mirapex, but my new
doctor did, in 3 months time, the changes were remarkable. I wonder if you ever heard of anything like this and what your opinion is about it.
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ThePharmacist
406 posts
Nov 09, 2009
8:22 PM
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I have heard alot of this. Many people on this forum, and elsewhere, have experienced the gambling, sexual, and obsessive behavior from this class of meds. When the dose is decreased or the med taken away, the symptoms subside. Best of health, Mark
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Judy52
1 post
Jan 28, 2010
6:06 AM
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I'm suspecting that the amount of salt I eat can interfere with the effectiveness of Mirapex. I take .5mg at night for RLS. On nights when I have had higher salt intake at supper (i.e. pizza) the Mirapex seems to aggravate the RLS rather than calm it. Is this typical or is it an adverse reaction that I should be concerned about?
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ThePharmacist
508 posts
Jan 29, 2010
10:01 PM
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when a person consumes alot of salt, they also retain water. Where there is excess salt in the system there is also excess water so the amount of medication you take is the same but the amount of "liquid" in to blood has increased, making the medication less effective. The excess water has diluted the medication. A good example is this:
Place a teaspoon of sugar in a 4oz glass of water and a teaspoon in an 8oz glass of water. Are they equally sweet? No. Even though they have the same amount of sugar (or mg if it were a tablet) the 8oz glass has a greater volume of water to sweeten.Hope you see what I mean. I probably made you more confused. Best of health, Mark
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