brooksie
9 post s
17-Feb-2008
9:55 PM
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I've read abstracts of several studies that indicate the seed pod of the plant mucuna pruriens, which contains dopamine, as more effective than the synthetic l-dopa. It has been used for at least a decade as an Aryuvedic PD treatment in India. I am all for trying "natural" treatments first. My questions: -Why aren't further studies on this promising treatment being pursued here? Is it because no patent can benefit a pharmaceutical company? -I plan to try this with the guidance of my neuro, but I am seeking a reputable supplier? Does anyone have any experience with this supplement?
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ellaauch
13 post s
4-Mar-2008
11:13 PM
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I tried it. I ordered it from Physicians Formula. The recommended dose on the bottle is far lower then the dose used in the clinical trials.
I looked up the minimal toxic and minimal lethal dose ( very high) and noticed that the study had stayed far below those. Then I slowly upped the dose from the recommended dose ( it is actually sold as a cure-all and for sexuall function). At the recommended dose there was no benefit. I used speed of finger tapping (index to thumb in 60sec) as my guide. At 8 capsules (3.2g) there was significant improvement. The study I read used 15 and 30g respectively- that is a huge amount. There where side effects and the effect not very sustained, rapid peak. A time release formula would be needed I think.
I was curious since I have undspecified MD- possible PD. So I figured if my symptoms are L-dopa responsive it would tell me alot. The National Parkinsons Association Web site has alot of info on mucuna. I think it has potential but needs to be developed into a standardized and time release formula.
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brooksie
17 post s
5-Mar-2008
10:56 AM
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Thanks for sharing your experience. What, may I ask, were the side effects? I've read it helps fertility too. My Neuro gave me the green light to try it, so I'll report back soon :-) I understand why, but I get so frustrated with how slow we are here to study natural treatments. I may even try an Aryuvedic Practioner.
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ThePharmacist
16 post s
16-May-2008
6:55 PM
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I truely think it is worth trying. The only issue I see is with the dose. How much would a person have to consume in order to get therapeutic levels in the blood/ brain? This is the big question. Best of health,
mark
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